Nepac Eye Drops 5ml (Nepafenac) – sante (private) limited

Used For

Eye Inflammation

How It Works

Nepafenac is a non-steroidal anti-inflammatory drug (NSAID) available as a prodrug. After being applied to the eye, it penetrates the cornea and is converted by ocular tissue hydrolases into its active form, amfenac. Amfenac works by blocking the cyclooxygenase (COX) enzyme, which is responsible for producing prostaglandins—substances that cause pain and inflammation. This helps reduce eye inflammation and discomfort.

Usage & Safety
Dosage

Instill one drop into the affected eye(s) three times daily—morning, afternoon, and evening. Use the drops at the same time each day or as directed by your physician.

Side Effects

Like all medicines, Nepafenac may cause side effects, although not everyone experiences them.

Eye-related side effects:

Eye pain or discomfort
Dry eyes
Eyelid swelling
Eye irritation
Itchy eyes
Eye discharge
Allergic conjunctivitis (eye allergy)
Increased tear production
Eye redness
Deposits on the surface of the eye
Swelling or fluid buildup at the back of the eye (macular edema)
Iris inflammation

General side effects:

Headache
Dizziness
Nausea
Allergic reactions, including eyelid swelling
Skin inflammation, redness, or itching
Drug Interactions

Inform your doctor or pharmacist if you are taking, have recently taken, or plan to take any other medicines. Nepafenac may interact with other eye drops, including medications used to treat glaucoma. Tell your doctor if you are using blood-thinning medicines such as warfarin or other NSAIDs, as these may increase the risk of bleeding.

Indications

Nepafenac Ophthalmic Suspension is indicated in adults for:

Prevention and relief of eye pain and inflammation following cataract surgery.
Reduction of the risk of macular edema (swelling at the back of the eye) after cataract surgery in diabetic patients.
When Not to Use

Do not use this medicine if:

You are allergic to Nepafenac or any of its ingredients.
You are allergic to other non-steroidal anti-inflammatory drugs (NSAIDs).
You have previously experienced asthma, severe skin allergies, or nasal inflammation after using NSAIDs such as aspirin (acetylsalicylic acid), ibuprofen, ketoprofen, piroxicam, or diclofenac.
Precautions

Topical NSAIDs may cause keratitis (inflammation of the cornea). In some patients, prolonged use may lead to corneal epithelial damage, corneal thinning, erosion, ulceration, or even corneal perforation, which may threaten vision. If signs of corneal damage occur, discontinue the medicine immediately and consult your eye specialist for close monitoring.

Warnings
Topical anti-inflammatory medicines may mask the signs of an acute eye infection. Since NSAIDs do not have antibacterial properties, they should be used with anti-infective medicines only under medical supervision.
Contact lenses are generally not recommended during the recovery period after cataract surgery. Wear them only if advised by your doctor.
This medicine is for ophthalmic use only. Do not inject or swallow the product.
Additional Information
Pregnancy

If you are pregnant, planning to become pregnant, or breastfeeding, consult your physician before using this medicine.

Storage

Store at room temperature, away from direct heat and sunlight. Keep the bottle tightly closed and out of the reach of children.

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